Puerto Ayora, Santa Cruz
The main hub. Best access, most choice, highest prices.
Puerto Ayora is where most visitors end up, and for good reason. Charles Darwin Avenue runs along the waterfront with dive shops, restaurants, and a fish market steps from the pier. The Charles Darwin Research Station sits 10 minutes east on foot. Buses to the highlands leave from Av. Baltra. Inter-island ferries depart from the Muelle Maritimo just off the main strip. Hotels range from concrete guesthouses one block inland to boutique waterfront properties. The town feels lived-in rather than resort-built. Most organized tours start here, giving you the widest flexibility for day trips to uninhabited islands. Expect street noise near the waterfront bars at night.
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